BDBM50261864 CHEMBL4100435

SMILES NC(=O)c1cc(Cl)c2c(Cl)c(C#CC3CC3)n(C3CCCNC3)c2n1

InChI Key InChIKey=MPFTYTXJRHGYBP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261864   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261864(CHEMBL4100435)
Affinity DataIC50:  75nMAssay Description:Inhibition of PIM1 in human KG1 cells assessed as reduction in BAD phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261864(CHEMBL4100435)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261864(CHEMBL4100435)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261864(CHEMBL4100435)
Affinity DataIC50:  6nMAssay Description:Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed