BDBM50261864 CHEMBL4100435
SMILES NC(=O)c1cc(Cl)c2c(Cl)c(C#CC3CC3)n(C3CCCNC3)c2n1
InChI Key InChIKey=MPFTYTXJRHGYBP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50261864
Affinity DataIC50: 75nMAssay Description:Inhibition of PIM1 in human KG1 cells assessed as reduction in BAD phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi Genzyme
Curated by ChEMBL
Sanofi Genzyme
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair