BDBM50261873 CHEMBL4070019

SMILES CN1CCC(CC1)n1c(I)c(Cl)c2c(Cl)cc(nc12)C(N)=O

InChI Key InChIKey=AHEMFHZQUVEVBH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50261873   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261873(CHEMBL4070019)
Affinity DataIC50:  2nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261873(CHEMBL4070019)
Affinity DataIC50:  34nMAssay Description:Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261873(CHEMBL4070019)
Affinity DataIC50:  6nMAssay Description:Inhibition of PIM3 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed