BDBM50261979 5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline::CHEMBL502351
SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12
InChI Key InChIKey=FVRYPYDPKSZGNS-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50261979
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of ALK-2 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 9.83E+3nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein 4(Mus musculus)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 152nMAssay Description:Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair