BDBM50262153 4-{2-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4-yl)-phenoxy]-ethyl}-morpholine::CHEMBL467154

SMILES Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1OCCN1CCOCC1

InChI Key InChIKey=HFUGPBREWMAERV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262153   

TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262153(4-{2-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4...)
Affinity DataKi:  28nMAssay Description:Antagonist activity at vassopressin V1a receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262153(4-{2-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50262153(4-{2-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4...)
Affinity DataKi:  304nMAssay Description:Displacement of [3H]-oxytocin from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50262153(4-{2-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4...)
Affinity DataKi:  304nMAssay Description:Antagonist activity at human cloned oxytocin receptor by cell based beta lactamase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed