BDBM50262257 CHEMBL4104005

SMILES NC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1N[C@H](CO)Cc1ccccc1

InChI Key InChIKey=KACCGMRCUUFUSQ-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262257   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50262257(CHEMBL4104005)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of JAK3 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50262257(CHEMBL4104005)
Affinity DataIC50:  19nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluorescent labelled IPTSPITTTYFFFKKK peptide as substrate after 60 mins by caliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed