BDBM50262330 CHEMBL4068127

SMILES CNC(=O)c1cnc(Nc2ccc(OC)cc2)cc1N[C@H]([C@H](O)CO)c1ccccc1

InChI Key InChIKey=TWSNMEUSGKKUHC-IRLDBZIGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262330   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50262330(CHEMBL4068127)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human fibroblast mitochondrial TK2 using dThd substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50262330(CHEMBL4068127)
Affinity DataIC50:  10nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluorescent labelled IPTSPITTTYFFFKKK peptide as substrate after 60 mins by caliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed