BDBM50262449 CHEMBL514706::N-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-2-methylbutan-2-yl)quinolin-3-amine

SMILES CC(C)(CCc1nc(no1)-c1ccc(F)cc1Cl)Nc1cnc2ccccc2c1

InChI Key InChIKey=PKAIHLUGFFKSDM-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262449   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50262449(CHEMBL514706 | N-(4-(3-(2-chloro-4-fluorophenyl)-1...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in insect Sf9 cells assessed as effect on Eu-GTP bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50262449(CHEMBL514706 | N-(4-(3-(2-chloro-4-fluorophenyl)-1...)
Affinity DataEC50:  53nMAssay Description:Agonist activity at human CB2 receptor expressed in insect Sf9 cells assessed as effect on Eu-GTP bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50262449(CHEMBL514706 | N-(4-(3-(2-chloro-4-fluorophenyl)-1...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human CB2 receptor assessed as inhibition of forskolin-induced increase in intracellular cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50262449(CHEMBL514706 | N-(4-(3-(2-chloro-4-fluorophenyl)-1...)
Affinity DataEC50: >2.00E+3nMAssay Description:Agonist activity at human CB1 receptor assessed as inhibition of forskolin-induced increase in intracellular cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed