BDBM50262664 CHEMBL504598::N-(5-benzylthiazol-2-yl)thiophene-2-carboxamide::cid_644846

SMILES O=C(Nc1ncc(Cc2ccccc2)s1)c1cccs1

InChI Key InChIKey=GCLLSWDNUPEMDW-UHFFFAOYSA-N

Data  1 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262664   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50262664(CHEMBL504598 | N-(5-benzylthiazol-2-yl)thiophene-2...)
Affinity DataKi:  90nMAssay Description:Inhibition of Abl kinase (unknown origin) by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50262664(CHEMBL504598 | N-(5-benzylthiazol-2-yl)thiophene-2...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM50262664(CHEMBL504598 | N-(5-benzylthiazol-2-yl)thiophene-2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50262664(CHEMBL504598 | N-(5-benzylthiazol-2-yl)thiophene-2...)
Affinity DataEC50:  1.08E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay