BDBM50263146 5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)-N-(4-morpholinophenyl)pyrimidin-2-amine::CHEMBL515001

SMILES CC(C)n1c(C)ncc1-c1nc(Nc2ccc(cc2)N2CCOCC2)ncc1F

InChI Key InChIKey=XCPITERAYNQRGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263146   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50263146(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50263146(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed