BDBM50263556 2-cyano-4-(2-cyclopentylethylamino)-N-methyl-6-((1-methylpiperidin-4-yl)methoxy)pyrimidine-5-carboxamide::CHEMBL478012

SMILES CNC(=O)c1c(NCCC2CCCC2)nc(nc1OCC1CCN(C)CC1)C#N

InChI Key InChIKey=ZEJPZPGMAWZAJD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263556   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50263556(2-cyano-4-(2-cyclopentylethylamino)-N-methyl-6-((1...)
Affinity DataIC50:  360nMAssay Description:Displacement of [3H]dofetilide from human ERG in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50263556(2-cyano-4-(2-cyclopentylethylamino)-N-methyl-6-((1...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50263556(2-cyano-4-(2-cyclopentylethylamino)-N-methyl-6-((1...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed