BDBM50263960 10-fluoro-2-hydroxy-7-(trifluoromethyl)-6,11-dihydro-5H-benzo[a]carbazole-3-carboxylic acid::CHEMBL490586

SMILES OC(=O)c1cc2CCc3c([nH]c4c(F)ccc(c34)C(F)(F)F)-c2cc1O

InChI Key InChIKey=VVXPIDMGMDCIEU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263960   

TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263960(10-fluoro-2-hydroxy-7-(trifluoromethyl)-6,11-dihyd...)
Affinity DataEC50:  799nMAssay Description:Agonist activity at human thrombopoietin receptor in Ba/F3 cells assessed as activation of Stat5 response element-driven reporter gene expressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed