BDBM50264391 CHEMBL523816::N-(6-aminopyridin-3-yl)-6-chloro-3-(3-(trifluoromethyl)phenylamino)benzo[d]isoxazole-7-carboxamide

SMILES Nc1ccc(NC(=O)c2c(Cl)ccc3c(Nc4cccc(c4)C(F)(F)F)noc23)cn1

InChI Key InChIKey=WVYGRJBDUQOBBG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264391   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50264391(CHEMBL523816 | N-(6-aminopyridin-3-yl)-6-chloro-3-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed