BDBM50266286 CHEMBL4650213

SMILES Oc1ccccc1C(=O)C=CN1C[C@H]2C[C@@H]1CN2c1ccccn1

InChI Key InChIKey=PKAHAABFUSYZKX-UHFFFAOYSA-N

Data  4 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50266286   

TargetProtein polybromo-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50266286(CHEMBL4650213)
Affinity DataIC50:  550nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription activator BRG1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50266286(CHEMBL4650213)
Affinity DataIC50:  411nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription activator BRG1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50266286(CHEMBL4650213)
Affinity DataKd:  89nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription activator BRG1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50266286(CHEMBL4650213)
Affinity DataIC50:  263nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein polybromo-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50266286(CHEMBL4650213)
Affinity DataKd:  48nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription activator BRG1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50266286(CHEMBL4650213)
Affinity DataIC50:  648nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed