BDBM50267254 4-[(4-Furan-2-yl-3-hydroxy-benzylamino)-methylene]-6-iodo-4Hisoquinoline-1,3-dione::CHEMBL477877

SMILES Oc1cc(CNC=C2C(=O)NC(=O)c3ccc(I)cc23)ccc1-c1ccco1

InChI Key InChIKey=LSLNBGJNQZNLSY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267254   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267254(4-[(4-Furan-2-yl-3-hydroxy-benzylamino)-methylene]...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267254(4-[(4-Furan-2-yl-3-hydroxy-benzylamino)-methylene]...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267254(4-[(4-Furan-2-yl-3-hydroxy-benzylamino)-methylene]...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK1/Cyclin B1 (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed