BDBM50267352 (-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methanol::CHEMBL513224

SMILES OC[C@H]1CN(Cc2ccccc2)CCCN1Cc1ccccc1

InChI Key InChIKey=WWYPEUUJEKQBLS-HXUWFJFHSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267352   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267352((-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methano...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267352((-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methano...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267352((-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methano...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radioligand from mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed