BDBM50267353 (-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diazepan-2-yl]methanol::CHEMBL518434

SMILES COC(CN1CCCN(Cc2ccccc2)[C@@H](CO)C1)OC

InChI Key InChIKey=DPWJZQJZQFPBJA-MRXNPFEDSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267353   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267353((-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diaz...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267353((-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267353((-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radioligand from mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed