BDBM50267775 (4-(3-(1H-pyrazol-5-yl)-5-(trifluoromethyl)phenylsulfonyl)piperazin-1-yl)((1R,2R)-2-(4-(trifluoromethyl)phenyl)cyclopropyl)methanone::CHEMBL487708

SMILES FC(F)(F)c1ccc(cc1)[C@@H]1C[C@H]1C(=O)N1CCN(CC1)S(=O)(=O)c1cc(cc(c1)C(F)(F)F)-c1cc[nH]n1

InChI Key InChIKey=FVKOQIAHRJRIQI-LEWJYISDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267775   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267775((4-(3-(1H-pyrazol-5-yl)-5-(trifluoromethyl)phenyls...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human ERG by MK0499 binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267775((4-(3-(1H-pyrazol-5-yl)-5-(trifluoromethyl)phenyls...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267775((4-(3-(1H-pyrazol-5-yl)-5-(trifluoromethyl)phenyls...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed