BDBM50267820 (4-(biphenyl-3-ylsulfonyl)piperazin-1-yl)(cyclohexyl)methanone::CHEMBL490043

SMILES O=C(C1CCCCC1)N1CCN(CC1)S(=O)(=O)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=PLDPMGKDBWCPST-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267820   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267820((4-(biphenyl-3-ylsulfonyl)piperazin-1-yl)(cyclohex...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267820((4-(biphenyl-3-ylsulfonyl)piperazin-1-yl)(cyclohex...)
Affinity DataEC50:  6nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267820((4-(biphenyl-3-ylsulfonyl)piperazin-1-yl)(cyclohex...)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed