BDBM50267968 CHEMBL4085945

SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]C1([#6])[#8]-c2c(-[#6])cc(-[#8])cc2-[#6]=[#6]1)-[#6](-[#8])=O

InChI Key InChIKey=QKXAGRZCXAYBQX-WDZAAMDOSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267968   

TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267968(CHEMBL4085945)
Affinity DataKi:  2.90E+3nMAssay Description:Noncompetitive inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267968(CHEMBL4085945)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267968(CHEMBL4085945)
Affinity DataIC50:  9.73E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267968(CHEMBL4085945)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed