BDBM50268015 CHEMBL4079935

SMILES COc1n[nH]c2ncc(cc12)C#Cc1c(F)ccc(NS(=O)(=O)c2cccc(OC)c2)c1F

InChI Key InChIKey=WJONPNKRHKNNAO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268015   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50268015(CHEMBL4079935)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of wild type GST-tagged recombinant human full-length B-RAF expressed in baculovirus expression system using Ser/Thr3 as substrate after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50268015(CHEMBL4079935)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full-length ZAK expressed in baculovirus infected Sf9 insect cells using MBP as substrate after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed