BDBM50268444 6-((3'-(dimethylamino)biphenyl-3-yl)methylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile::CHEMBL495803

SMILES CN(C)c1cccc(c1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1

InChI Key InChIKey=KRPQJLQXOMQLEZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268444   

TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50268444(6-((3'-(dimethylamino)biphenyl-3-yl)methylamino)-9...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50268444(6-((3'-(dimethylamino)biphenyl-3-yl)methylamino)-9...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of California

Curated by ChEMBL
LigandPNGBDBM50268444(6-((3'-(dimethylamino)biphenyl-3-yl)methylamino)-9...)
Affinity DataIC50:  900nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed