BDBM50268562 CHEMBL497616::N-Hydroxy-N-[3-(3-(3,4-dichlorophenoxy)phenyl)propyl]phosphonoacetamide Dipotassium Salt

SMILES ON(CCCc1cccc(Oc2ccc(Cl)c(Cl)c2)c1)C(=O)CP([O-])([O-])=O

InChI Key InChIKey=WJTDBJKLODQVOB-UHFFFAOYSA-L

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268562   

Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50268562(CHEMBL497616 | N-Hydroxy-N-[3-(3-(3,4-dichlorophen...)
Affinity DataKi:  320nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50268562(CHEMBL497616 | N-Hydroxy-N-[3-(3-(3,4-dichlorophen...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed