BDBM50269455 CHEMBL4087402
SMILES Cl.COc1cc(F)ccc1C1CN(CCN1)c1nc(cc(=O)n1C)-c1ccncc1
InChI Key InChIKey=OLFIUQHGRNUZGL-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50269455
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >5.30E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >5.30E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
Affinity DataIC50: >5.30E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >5.30E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair