BDBM50270667 CHEMBL4130194

SMILES CC(Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3ccccc3c2=O)CC1

InChI Key InChIKey=BAMWYPCZJUTPAE-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50270667   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50270667(CHEMBL4130194)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of USP7 (unknown origin) using GST-Ub52-flag substrate incubated for 1 hr by fluorimetryMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50270667(CHEMBL4130194)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of recombinant full length USP7 (unknown origin) using ubiquintin-rhodamine as substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270667(CHEMBL4130194)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 47(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270667(CHEMBL4130194)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of USP47 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270667(CHEMBL4130194)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of His6-tagged human USP1 expressed in insect Sf21 cells coexpressing untagged UAF1 assessed as cleavage of Ubiquitin-Rhodamine110-glycine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed