BDBM50270783 CHEMBL508411::QRFCTGHFGGLYPCNGP

SMILES CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O

InChI Key InChIKey=BEWHODOAEGZIDE-YNALCKGOSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50270783   

TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270783(CHEMBL508411 | QRFCTGHFGGLYPCNGP)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human IgG binding to soluble human FcRn by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270783(CHEMBL508411 | QRFCTGHFGGLYPCNGP)
Affinity DataKd:  4.50E+4nMpH: 7.4Assay Description:Binding affinity to human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270783(CHEMBL508411 | QRFCTGHFGGLYPCNGP)
Affinity DataKd:  5.70E+3nMpH: 6.0Assay Description:Binding affinity to human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed