BDBM50271441 CHEMBL505502::Tyr-Pro-Phe-Phe-OCH2CH3

SMILES CCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=JKMFJIMTIXQDHF-KRCBVYEFSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50271441   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271441(CHEMBL505502 | Tyr-Pro-Phe-Phe-OCH2CH3)
Affinity DataKi:  15.0nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50271441(CHEMBL505502 | Tyr-Pro-Phe-Phe-OCH2CH3)
Affinity DataKi:  15nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50271441(CHEMBL505502 | Tyr-Pro-Phe-Phe-OCH2CH3)
Affinity DataKi:  2.94E+3nMAssay Description:Binding affinity to DOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271441(CHEMBL505502 | Tyr-Pro-Phe-Phe-OCH2CH3)
Affinity DataKi:  2.94E+3nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271441(CHEMBL505502 | Tyr-Pro-Phe-Phe-OCH2CH3)
Affinity DataIC50:  63.8nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Cavia porcellus)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271441(CHEMBL505502 | Tyr-Pro-Phe-Phe-OCH2CH3)
Affinity DataIC50:  64.4nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed