BDBM50271442 CHEMBL500195::Tyr-Pro-Phe-Phe-OC(CH3)3

SMILES CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=MUCJBMLSOAIPBH-ORYMTKCHSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50271442   

TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50271442(CHEMBL500195 | Tyr-Pro-Phe-Phe-OC(CH3)3)
Affinity DataKi:  50nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271442(CHEMBL500195 | Tyr-Pro-Phe-Phe-OC(CH3)3)
Affinity DataKi:  50.4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50271442(CHEMBL500195 | Tyr-Pro-Phe-Phe-OC(CH3)3)
Affinity DataKi:  247nMAssay Description:Binding affinity to DOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271442(CHEMBL500195 | Tyr-Pro-Phe-Phe-OC(CH3)3)
Affinity DataKi:  247nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271442(CHEMBL500195 | Tyr-Pro-Phe-Phe-OC(CH3)3)
Affinity DataIC50:  74.1nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Cavia porcellus)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271442(CHEMBL500195 | Tyr-Pro-Phe-Phe-OC(CH3)3)
Affinity DataIC50:  3.00E+3nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed