BDBM50271458 CHEMBL3559789::US11225469, Compound 30
SMILES FC(F)(F)c1cccc(c1)N1CCN(CC1)C(=S)Nc1cccnc1
InChI Key InChIKey=CYBXHIBLYZFAMJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50271458
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research
US Patent
Whitehead Institute For Biomedical Research
US Patent
Affinity DataIC50: <5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research
US Patent
Whitehead Institute For Biomedical Research
US Patent
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair