BDBM50272192 4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1H)-one::CHEMBL501724
SMILES Cc1cc(ccc1O)-c1cc(nc(=O)[nH]1)-c1ccccc1
InChI Key InChIKey=MHPMAOLCNNEBOA-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50272192
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research
Curated by ChEMBL
Novartis Institutes Of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of CDC7-DBF4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >5.28E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 332nMAssay Description:Inhibition of N-terminus His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research
Curated by ChEMBL
Novartis Institutes Of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of N-terminus Myc-tagged human CDC7 expressed in Escherichia coli by chemiluminescence assay in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 17.2nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair