BDBM50272627 CHEMBL4126644

SMILES Nc1c2CCCCc2nc2cccc(N3CCN(CCCCc4c[nH]c5ccc(cc45)C#N)CC3)c12

InChI Key InChIKey=LAMAZEAPYUFTOT-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272627   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50272627(CHEMBL4126644)
Affinity DataEC50:  0.360nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK293 cells after 60 mins by Eu-cAMP solution based ultra LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50272627(CHEMBL4126644)
Affinity DataIC50:  340nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate after 20 mins by by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50272627(CHEMBL4126644)
Affinity DataIC50:  20nMAssay Description:Inhibition of SERT (unknown origin) expressed in HEK293 cells assessed as reduction in 5-HT uptake incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50272627(CHEMBL4126644)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 20 mins by by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed