BDBM50272667 (R)-5-(3-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(dimethylamino)-2-phenylethyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-fluorophenoxy)pentanoic acid::CHEMBL509267

SMILES CN(C)[C@@H](Cn1c(=O)c(c(C)n(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1cccc(OCCCCC(O)=O)c1F)c1ccccc1

InChI Key InChIKey=NSBUNJVFFBYJER-MHZLTWQESA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272667   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272667((R)-5-(3-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-3...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]Pro-N-Et-GnRH from human cloned GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272667((R)-5-(3-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-3...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) by microtiter plate-based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed