BDBM50272679 4-[2-(1-Methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-2-carbonitrile::CHEMBL496657

SMILES CN1CCC(CCOc2cc(NCC3CCC4(CC4)CC3)nc(n2)C#N)CC1

InChI Key InChIKey=IXULIQOVYWLEAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272679   

TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50272679(4-[2-(1-Methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50272679(4-[2-(1-Methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2...)
Affinity DataIC50:  870nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50272679(4-[2-(1-Methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human recombinant cathepsin K by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed