BDBM50272803 3-[((8S)-8-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino}-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-2-yl)oxy]benzoic Acid::CHEMBL498531

SMILES O[C@@H](CN[C@H]1CCCc2ccc(Oc3cccc(c3)C(O)=O)cc2C1)c1cccc(Cl)c1

InChI Key InChIKey=OYBYKWZIDBDHAI-DHLKQENFSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272803   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50272803(3-[((8S)-8-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethy...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50272803(3-[((8S)-8-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethy...)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50272803(3-[((8S)-8-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethy...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed