BDBM50274036 CHEMBL4128478

SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](Cc1ccc(CN)cc1)CS(F)(=O)=O

InChI Key InChIKey=KESUUTGCAABDAJ-LJWNLINESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274036   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274036(CHEMBL4128478)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274036(CHEMBL4128478)
Affinity DataIC50:  130nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274036(CHEMBL4128478)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274036(CHEMBL4128478)
Affinity DataIC50:  130nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed