BDBM50274723 CHEMBL458622::N-Formyl-D-leucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester

SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H](CC(C)C)NC=O

InChI Key InChIKey=AHLBNYSZXLDEJQ-NFGXINMFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50274723   

TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50274723(CHEMBL458622 | N-Formyl-D-leucine-(1S)-1-[[(2S,3S)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant DAGLalpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50274723(CHEMBL458622 | N-Formyl-D-leucine-(1S)-1-[[(2S,3S)...)
Affinity DataIC50:  15nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50274723(CHEMBL458622 | N-Formyl-D-leucine-(1S)-1-[[(2S,3S)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FAAH-mediated [14C]anadamide hydrolysis in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed