BDBM50274743 CHEMBL458547::N-(2-methoxyethyl)-4-(4-(1,2,4-trimethyl-1H-imidazol-5-yl)pyrimidin-2-ylamino)benzenesulfonamide

SMILES COCCNS(=O)(=O)c1ccc(Nc2nccc(n2)-c2c(C)nc(C)n2C)cc1

InChI Key InChIKey=LGCAIPXMWBZXAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274743   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50274743(CHEMBL458547 | N-(2-methoxyethyl)-4-(4-(1,2,4-trim...)
Affinity DataIC50: >8.60E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50274743(CHEMBL458547 | N-(2-methoxyethyl)-4-(4-(1,2,4-trim...)
Affinity DataIC50:  68nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed