BDBM50275847 (R)-3-Amino-N-(1,1-dioxo-4-phenyl-hexahydro-1lambda*6*-thiopyran-4-yl)-4-(2-fluoro-phenyl)-butyramide::CHEMBL512145

SMILES N[C@@H](CC(=O)NC1(CCS(=O)(=O)CC1)c1ccccc1)Cc1ccccc1F

InChI Key InChIKey=NQFGLOAYMPJLSZ-GOSISDBHSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50275847   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275847((R)-3-Amino-N-(1,1-dioxo-4-phenyl-hexahydro-1lambd...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human Caco2 cells-derived DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275847((R)-3-Amino-N-(1,1-dioxo-4-phenyl-hexahydro-1lambd...)
Affinity DataIC50:  2.84E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275847((R)-3-Amino-N-(1,1-dioxo-4-phenyl-hexahydro-1lambd...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275847((R)-3-Amino-N-(1,1-dioxo-4-phenyl-hexahydro-1lambd...)
Affinity DataIC50:  570nMAssay Description:Inhibition of DPP4 in human Caco2 cell extracts using Ala-Pro-AFC as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275847((R)-3-Amino-N-(1,1-dioxo-4-phenyl-hexahydro-1lambd...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed