BDBM50276096 CHEMBL4125940
SMILES COc1cc(Nc2ncc3c(n2)n(-c2cccc(NC(=O)C=C)c2)c(=O)n(C(C)C)c3=O)ccc1N1CCN(C)CC1
InChI Key InChIKey=YASVHHAMJUVDDP-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50276096
TargetEpidermal growth factor receptor(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system using Poly(Glu,Tyr)4:1 as substrate...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
East China University Of Science & Technology
Curated by ChEMBL
East China University Of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BTK (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R/T790M double mutant expressed in baculovirus expression system using Poly(Glu,Tyr)4:1 as substr...More data for this Ligand-Target Pair