BDBM50277158 3123L::CHEBI:17939::CL-13900::GNF-Pf-2016::P-638::Puromycin::TCMDC-123493
SMILES COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1
InChI Key InChIKey=RXWNCPJZOCPEPQ-NVWDDTSBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50277158
TargetPuromycin-sensitive aminopeptidase(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Russian Academy Of Sciences
Curated by ChEMBL
Russian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.80E+7nMAssay Description:Inhibition of human N-terminal His-tagged TDP1 expressed in Escherichia coli BL21 using [32P]-D14Y duplex DNA as substrate incubated for 20 mins by P...More data for this Ligand-Target Pair
TargetPuromycin-sensitive aminopeptidase(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
TargetAminopeptidase N(Sus scrofa (Pig))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 minsMore data for this Ligand-Target Pair