BDBM50277161 CHEMBL4166095

SMILES Oc1ccc(\C=C\C(=O)c2cccnc2)cc1O

InChI Key InChIKey=FGVWMVPACIUGMM-HWKANZROSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277161   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50277161(CHEMBL4166095)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibition of GSK3beta (unknown origin) using GSM substrate after 30 mins by Kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50277161(CHEMBL4166095)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition recombinant human TG2 using N-CbzGlu(gamma-p-nitrophenylester)Gly as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50277161(CHEMBL4166095)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation by thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed