BDBM50277192 4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylphenylsulfonyl)morpholine::CHEMBL474896

SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nc(CC2CCCCC2)cs1

InChI Key InChIKey=OGNXMBCUTKGOQT-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50277192   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50277192(4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylph...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50277192(4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylph...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50277192(4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylph...)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]CP55940 from human cloned CB1 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50277192(4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylph...)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50277192(4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylph...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed