BDBM50277281 4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)phenyl)isothiazole-3-carboxamide::CHEMBL515880
SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
InChI Key InChIKey=QTSMTVDWAMIJBE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50277281
Affinity DataKi: 130nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC90 concentration by ATP based competition assayMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC50 concentration by ATP based competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of VEGFR1 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISAMore data for this Ligand-Target Pair