BDBM50277602 CHEMBL4164283

SMILES CNc1nc(C)c(s1)-c1ccnc(Nc2ccc(OC)cc2OC)n1

InChI Key InChIKey=FYSLUTGZWHZPCX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277602   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of South Australia

Curated by ChEMBL
LigandPNGBDBM50277602(CHEMBL4164283)
Affinity DataKi:  32nMAssay Description:Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia

Curated by ChEMBL
LigandPNGBDBM50277602(CHEMBL4164283)
Affinity DataKi:  110nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of South Australia

Curated by ChEMBL
LigandPNGBDBM50277602(CHEMBL4164283)
Affinity DataKi:  1.47E+3nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed