BDBM50277813 (3R,4R)-2-methyl-1-oxo-3-(4-phenoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid::CHEMBL485025

SMILES CN1[C@H]([C@H](C(O)=O)c2ccccc2C1=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=JDYIMYZYEPQLHV-RTWAWAEBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277813   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50277813((3R,4R)-2-methyl-1-oxo-3-(4-phenoxyphenyl)-1,2,3,4...)
Affinity DataIC50:  156nMAssay Description:Antagonist activity at human GPR40 expressed HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed