BDBM50278609 CHEMBL470011::N7-(3-chloro-4-fluorophenyl)-N2-(4-(piperidin-1-ylmethyl)phenyl)thiazolo[4,5-d]pyrimidine-2,7-diamine

SMILES Fc1ccc(Nc2ncnc3nc(Nc4ccc(CN5CCCCC5)cc4)sc23)cc1Cl

InChI Key InChIKey=DLMNHRYJMPUZPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278609   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278609(CHEMBL470011 | N7-(3-chloro-4-fluorophenyl)-N2-(4-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed