BDBM50278970 CHEMBL4175914

SMILES COc1ccccc1CNCCCCCCNC(=O)c1cc(Cl)nc(Cl)c1

InChI Key InChIKey=IRZDPXVHGNXLGP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278970   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50278970(CHEMBL4175914)
Affinity DataKi:  355nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50278970(CHEMBL4175914)
Affinity DataIC50:  4.55E+4nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50278970(CHEMBL4175914)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed