BDBM50279649 CHEMBL4165323

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2c(CN(CC(N)=O)C1=O)ccc1ccccc21

InChI Key InChIKey=VRLMPUXFAPNKKK-IARZGTGTSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50279649   

TargetMu-type opioid receptor(GUINEA PIG)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279649(CHEMBL4165323)
Affinity DataIC50:  0.252nMAssay Description:Agonist activity at mu-opioid receptor in guinea pig ileum assessed as inhibition of electrically induced contractionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279649(CHEMBL4165323)
Affinity DataIC50:  1nMAssay Description:The compound was tested for inhibition of rabbit plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279649(CHEMBL4165323)
Affinity DataIC50:  1.40nMAssay Description:Agonist activity at delta-type opioid receptor in mouse vas deferens assessed as inhibition of electrically stimulated contractionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279649(CHEMBL4165323)
Affinity DataIC50:  0.330nMAssay Description:Displacement of [125I]-DAMGO from mouse FLAG-tagged Mu-type opioid receptor expressed in HEK293 cell membranes after 60 mins by gamma counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed