BDBM50280369 CHEMBL4169114
SMILES CCOc1ccc(cc1OC)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1
InChI Key InChIKey=YVBPGGPLSRCXIM-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50280369
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 513nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair