BDBM50281701 1-(4-Chloro-phenyl)-3-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea::CHEMBL355092

SMILES CN1c2ccccc2C(=N[C@H](NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1

InChI Key InChIKey=NKXJTSZBOBZLTH-OAQYLSRUSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50281701   

TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281701(1-(4-Chloro-phenyl)-3-((S)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50:  410nMAssay Description:Tested for its activity to inhibit the binding of [125I]-CCK-33 to Cholecystokinin type B receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281701(1-(4-Chloro-phenyl)-3-((S)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50:  410nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50281701(1-(4-Chloro-phenyl)-3-((S)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50:  26nMAssay Description:Tested for its activity to inhibit the binding of [125I]-CCK-33 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281701(1-(4-Chloro-phenyl)-3-((S)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50:  540nMAssay Description:Tested for its activity to inhibit the binding of [125I]-gastrin to gastric glands (gastrin) in guinea pigMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50281701(1-(4-Chloro-phenyl)-3-((S)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50281701(1-(4-Chloro-phenyl)-3-((S)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50:  110nMAssay Description:Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281701(1-(4-Chloro-phenyl)-3-((S)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50:  540nMAssay Description:Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281701(1-(4-Chloro-phenyl)-3-((S)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed