BDBM50282208 CHEMBL4177314

SMILES CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)c1c(OCc2ccnc(c2)-c2ccccc2)c2ccccc2n(C)c1=O

InChI Key InChIKey=BWUYFLFXKOJQRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282208   

TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282208(CHEMBL4177314)
Affinity DataIC50:  16nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase obtained from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282208(CHEMBL4177314)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of full length C-terminal FLAG tagged human SMS1 expressed in HEK293 cell membranes using DMPC-d72 and C17-ceramide as substrate preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed